Dr. Ryan C.N. D'Arcy, Ph.D. Neuroscience Research
Primary contact: Please find out more at BrainNET
The focus of our research is on basic and clinical neuroscience, with both intertwined where possible through advanced medical technologies. We use a wide array of advanced brain imaging modalities to study functional neural systems and help patients with neurological and mental health conditions.
Fundamental science: Brain function is similar to weather systems. It emerges from complex neural networks and is dynamic across space, time, and other dimensions. Consequently, a multimodal imaging approach is needed to integrate and understand human brain function through non-invasive medical technologies. Technologies and methods include:
· High field magnetic resonance imaging (MRI)
· Functional magnetic resonance imaging (fMRI)
· Magnetic resonance spectroscopy (MRS)
· High-density magnetoencephalography (MEG)
· Magnetic source imaging (MSI)
· High-density electroencephalography (EEG)
· Current source imaging (CSI)
· Evoked and event-related potentials (EPs/ERPs)
· Rapid transcranial magnetic stimulation (TMS)
· Transcranial direct current stimulations (TDCS)
· Portable neuro-modulatory stimulation
· High performance computing and AI
Translational science: Advances in neurotechnologies enable the development of next-generation diagnostics and therapeutics for brain health. Overcoming the challenges and barriers to clinical implementation requires a focus on translational neuroscience. Advanced clinical applications include:
· Brain vital signs PoC evaluation and monitoring: NeuroCatch
· Functional monitoring of neuroplasticity: Rehabilitation / Project Iron Soldier
· Functional status evaluation: Halifax Consciousness Scanner (HCS)
· Perioperative PoC surgical simulation and training: PeriopSim
· Neurosurgical VR surgical simulation and training: NeuroTouch
· Functional brain mapping: Surgical and radiation treatment
· Biomarkers for early diagnoses: Brain Atrophy and Lesion Index (BALI)
· Brain health monitoring and optimization: Brain Power Score
· Advanced limits of functional imaging: White matter fMRI
Translational advances in neuroimaging / neurotechnologies have significant impacts across neurological, neurosurgical, and mental health domains. Clinical brain disorders and diseases include:
· Concussion and traumatic brain injury (TBI)
· Stroke and related cerebrovascular diseases
· Seizure disorders and epilepsy
· Alzheimer’s disease and related dementia
· Multiple sclerosis and related white matter diseases
· Parkinson’s disease and related movement disorders
· Primary and secondary brain tumours
· Autism and related developmental disorders
· Anxiety, depression, and related mood disorders
· Health brain optimization