Research
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Overview
I work on developing techniques for solving real-world clinical problems
through the automated processing and analysis
of multi-dimensional biomedical structural and functional images such as magnetic resonance imaging
(MRI, fMRI, DT-MRI) and computed tomography (X ray-CT, PET, SPECT),
and ultrasound. My research focuses on developing techniques for: segmentation
and registration, tracking and matching, shape representation
and deformation analysis of anatomical structures and functional regions in medical images. I also
work on building statistical, physical, and geometrical models of shape
variation and on their application to automated detection of structural
abnormality and pathology. I am also researching the development of controlled shape deformation techniques, and the
incorporation of context-based, artificially intelligent mechanisms for image
registration and segmentation using artificial life models.
Research Components
- Clinical Applications (e.g. cardiology, neurology,
oncology, and musculoskeletal)
- Medical Imaging Modalities (e.g. MRI, CT, ultrasound,
nuclear,, 2D, 3D, 3D+time, scalar, vector, tensor fields)
- Image processing (e.g. image filtering, enhancement, noise
reduction, edge detection)
- Image segmentation (e.g. identifying anatomical structures of
interest in medical images for quantification, visualization)
- Image Registration and Surface Matching (e.g. fusion of
medical images of different modalities, establishing correspondence
between images and shapes)
- Statistical Shape Analysis (e.g. 3d shape representation,
modeling anatomical shape variability, detecting shape abnormalities)
- Software Tools (see examples)
Keywords
- medical image analysis
- image segmentation, image registration, shape analysis,
- deformable models, geometric modeling,
- physics-based shape modeling, statistical shape modeling,
- artificial life
- medical imaging
- small animal image analysis
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